Miller was born in Manhattan, the daughter of model Bonnie Trompeter.1 Miller was a model as a child, appearing in a Wonder Bread commercial when she was six months old, posing at three for Francesco Scavullo in an Ivory soap advertisement, and being photographed for the cover of Redbook.citation needed Her days as a child model were curtailed after an operation for a benign bone tumor. After attending Convent of the Sacred Heart, she returned briefly to modeling, but soon took acting lessons, and gave up modeling when she moved to Los Angeles, California, in 1990.1 She was in the first U.S. edition of Maxim.
In 2001, Miller's husband, writer-producer Bill Lawrence, conceived a new comedy-drama, Scrubs. Miller was given a guest role as Dr. Cox's (John C. McGinley) acerbic ex-wife Jordan Sullivan. Originally, the character was intended to appear in only one episode; in season 2, the role became recurring. When her young cousin Teddy Ebersol, son of Susan St. James and Dick Ebersol, died in a plane crash in 2004, Scrubs dedicated the season 4 episode "My Lucky Charm" to him.
She now appears on Cougar Town, a sitcom created and produced by her husband, which stars Courteney Cox, with whom Miller worked in a three-part story-arc of Season 8 of Scrubs.
Personal life
Miller married Bill Lawrence in 1999.2 They have three children, Charlotte Sarah (born June 8, 2000), William Stoddard (born January 3, 2003), and Henry Vanduzer (born October 8, 2006). Her last two pregnancies were written into Scrubs.